Clinical efficacy of low molecular heparin on unexplained recurrent spontaneous abortion

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Evaluation of the Efficacy of Aspirin and Low Molecular Weight Heparin in Patients with Unexplained Recurrent Spontaneous Abortions

Background: The roles of inflammatory cytokines and local placental thrombosis in patients with unexplained recurrent spontaneous abortion (URSA) have been shown. Since low molecular weight heparin (LMWH) and acetyl salicylic acid (ASA) have both anti-inflammatory and anti-coagulant effect, we evaluated their efficacy in patients with URSA. Methods: One hundred patients with a history of URSA r...

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Low molecular weight heparin use in unexplained recurrent miscarriage

OBJECTIVE The aim of the study was to investigate whether the use of low molecular weight heparin (LMWH) improve live birth rates when compared with control group in patients with unexplained recurrent miscarriages (URM). METHODS In this prospective observational study 150 women with a history of two or more previous unexplained first trimester pregnancy loss who received LMWH; either enoxapa...

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P-157: TLR5 Gene Expression in Endometrium of Women with Unexplained Recurrent Spontaneous Abortion

Background: Recurrent spontaneous abortion (RSA) is usually defined as three or more consecutive pregnancy losses before 20th week of gestation. Although different factors are considered as etiology of RSA but in some cases, despite of extensive work up, the cause of RSA remains unknown which called unexplained RSA. Immunological factors are suggested as etiological factors of unexplained RSA. ...

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O-26: The Value of Hysteroscopy in Diagnosis of Chronic Endometritis in Patients with Unexplained Recurrent Spontaneous Abortion

Background: We performed this study in order to investigate the role of chronic endometritis (CE) in unexplained recurrent spontaneous abortion (RSA) and to determine the correlation between hysteroscopic and histologic findings of CE in patients with unexplained RSA. We also tried to find out the relation between CE and primary vs. secondary RSA. Materials and Methods: One hundred and forty-two ...

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Comparing Serum Levels of Th17 and Treg Cytokines in Women with Unexplained Recurrent Spontaneous Abortion and Fertile Women

Background: Increased evidences have shown that unexplained recurrent spontaneous abortion (URSA) is associated with inflammatory responses and breakage of immunological autotolerance. Therefore, the balance between Th17 and Treg cells may elucidate the pathophysiology of URSA. Objective: To investigate the serum concentration of regulatory and inflammatory cytokines associated with Treg and Th...

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ژورنال

عنوان ژورنال: Biomedical Research

سال: 2018

ISSN: 0976-1683

DOI: 10.4066/biomedicalresearch.29-17-3483